Hi: I am new to this board. I've had crohn's colitis for 8 years, been on everything --- bad bad reactions to many medications including asacol and 6mp. I just started Humira two weeks ago (did my second injection last night), and was wondering how it takes to kick in. I know they say 2 weeks to 3 months, but am wondering how long it took for others. Getting very sick of waiting and wondering if I should go back on Pred while waiting, but Yuk! Thanks for your replies. Debbie